Symptomatic Evaluation of Ayurvedic Formulation Panchatikta Ghrita Guggulu (PTK-G) used in Eczema in Bangladesh

Abstract

Ayurveda is one the oldest healing system in the world originated in India and is also native to Bangladesh, and more than 300 compound formulations are available commercially in Bangladesh. Panchatikta Ghrita Guggulu (PTK-G) is one of the leading products in Bangladesh used for skin disease as well as many other ailments through the efficacy data are lacking due to a few studies on it, especially in Bangladesh. The aim of the study was to find out the effectiveness of symptomatic evaluation. A quantitative pre-test and post-test study were designed and 20 eczema patients of both sexes were selected quasi-randomly from Kaliakoire, Gazipur, Bangladesh in 2014 and administered 500 mg capsule 3 times a day for 6 weeks.  Demographic pattern, itching, vesicle formation, oozing, fissure, swelling of a lesion, and size of the lesion were measured, and pictorial evaluation was done before and after the study. The prevalence is higher in female patients than in males i.e 70 % of female patients suffer from eczema. Lesion size was improved by 69.47% which was statistically significant (p=0.002). There were 90.23%, 55.75%, 86.40%, 81.34%, and 76.84% decreases noted in itching, vesicle formation, oozing, fissure, and swelling respectively which were statistically significant.

Throughout the experiment, it may be assumed that PTK-G is an effective drug for eczema, though the effects are not clearly visible and required further study on large scale.